YourSci.com is pretty slick
Yoursci.com is a Science 2.0 project along the lines of OpenWetWare, but with a little tighter focus. They’ve got a section for contributing a project, and protocol section, and what I particularly like, a negative data section.
Content contribution and tool making kinda trade off one another, but all too often the cycle breaks not because the tool isn’t functional, but because it’s ugly. YourSci.com is pretty, looks functional, and it just so happens that I have some information they’re looking for.